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sonata
Sonata belongs to the class of drugs called hypnotics, and is used for the short term treatment of sleep problems (insomnia). Hypnotics should generally be limited to 7 to 10 days of use. Reevaluation is recommended if hypnotics are taken for more than 2 to 3 weeks.
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SONATA
DRUG INFO
IMPORTANT
NOTE: The following information is intended
to supplement, not substitute for, the expertise
and judgment of your physician, pharmacist or
other healthcare professional. It should not
be construed to indicate that use of the drug
is safe, appropriate, or effective for you.
Consult your healthcare professional before
using this drug.
ZALEPLON - ORAL
(ZALL-eh-plon)
COMMON BRAND NAME(S):
Sonata
USES: This
sonata is used for the short-term treatment
of sleep problems (insomnia).
HOW TO USE:
Take this product by mouth, immediately
before bedtime or after you have gone to bed
and have difficulty sleeping, as directed by
your doctor. Do not take this sonata with,
or immediately after, a high-fat or heavy meal.
This sonata helps you fall asleep. To minimize
SIDE EFFECTS while you are awake (e.g., dizziness
or memory trouble), take this sonata when
you are in bed and are able to get at least
four hours of sleep before you need to be active
again. Do not use this sonata for longer
than ten days without your doctor's approval.
If your sleep problems continue, consult with
your doctor. Use this sonata exactly as
prescribed. Do not increase your dose, take
it more frequently or use it for a longer period
of time than prescribed because this drug can
be habit-forming. Also, if used for a longer
period of time, do not stop using this sonata
without your doctor's approval.
SIDE EFFECTS:
Headache, drowsiness, nausea or stomach upset
may occur. If any of these effects persist or
worsen, notify your doctor promptly. Tell your
doctor immediately if you have any of these
serious SIDE EFFECTS: dizziness, weakness, loss
of coordination, muscle joint pain. Tell your
doctor immediately if you have any of these
unlikely but serious SIDE EFFECTS: mental/mood
changes, persistent trouble sleeping, memory
problems, loss of appetite, tingling of the
hands or feet, rash, itching, tremors, eye/ear
problems. Tell your doctor immediately if you
have any of these very unlikely but serious SIDE EFFECTS: fast/slow/irregular pulse, chest
pain, trouble breathing, blood in the stool,
unusual thirst, change in amount of urine. If
you notice other effects not listed above, contact
your doctor or pharmacist.
PRECAUTIONS :
Tell your doctor your medical history, including:
allergies, liver disease, lung/breathing problems,
mental/mood problems (e.g., depression), alcohol
use or drug dependence. Avoid alcohol, as it
may aggravate certain SIDE EFFECTS of this drug
(e.g., dizziness, drowsiness). Use caution when
performing tasks requiring alertness (e.g.,
driving). You may have trouble sleeping the
first few nights after you stop using this sonata.
This problem usually goes away after one or
two nights. If sleep problems persist, consult
with your doctor. Use with caution in the elderly,
as they may be more sensitive to the effects
of this sonata. This sonata should be
used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.
This sonata passes into breast milk. Because
of the potential risk to the infant, breast-feeding
while using this sonata is not recommended.
Consult your doctor before breast- feeding.
DRUG INTERACTIONS: Tell your doctor of
all prescription and nonprescription sonata
you may use, especially of: rifamycin antibiotics
(e.g., rifampin, rifabutin), antidepressants
(e.g., imipramine, amitriptyline), ulcer sonata
(e.g., cimetidine). Also report any drugs causing
drowsiness such as: other medicines for sleep,
sedatives, tranquilizers, anti-anxiety drugs,
narcotic pain relievers (e.g., codeine), psychiatric
sonatas (e.g., thioridazine), anti-seizure
sonatas (e.g., phenytoin, phenobarbital,
carbamazepine), muscle relaxants, antihistamines
that cause drowsiness (e.g., diphenhydramine).
Check all medicine labels carefully, especially
cough-and-cold preparations, since many contain
antihistamines (e.g., diphenhydramine). Consult
your pharmacist regarding safe use of these
products. Do not start or stop any medicine
without doctor or pharmacist approval.
OVERDOSE: If OVERDOSEis suspected, contact your local poison
control center or emergency room immediately.
Symptoms If OVERDOSEmay include drowsiness;
confusion; sluggishness; loss of coordination;
slow, shallow breathing; and loss of consciousness.
NOTES : Do not
share this sonata with others.
MISSED DOSE :
Not applicable.
STORAGE : Store
at room temperature between 68 and 77 degrees
F (20 to 25 degrees C) away from light and moisture.
Zaleplon is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.
The chemical name of zaleplon is
N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide. Its
empirical formula is C17H15N5O, and its molecular weight is 305.34. The
structural formula is shown below.

Zaleplon is a white to off-white powder that is practically insoluble in
water and sparingly soluble in alcohol or propylene glycol. Its partition
coefficient in octanol/water is constant (log PC = 1.23) over the pH range of 1
to 7.
Sonata?capsules contain zaleplon as the active ingredient. Inactive
ingredients consist of microcrystalline cellulose, pregelatinized starch,
silicon dioxide, sodium lauryl sulfate, magnesium stearate, lactose, gelatin,
titanium dioxide, D&C yellow #10, FD&C blue #1, FD&C green #3, and
FD&C yellow #5.
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