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Overview
Valtrex is commonly used for the treatment of genital herpes. Valtrex is not a cure but will help sores heal faster and relieve pain or discomfort.
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More than 45 million Americans between the ages of 15 and 74 have the virus that causes genital herpes. That is one in every five people!
VALTREX?is the only once-a-day prescription medication proven to suppress future genital herpes outbreaks.
Valtrex®
(VALACYCLOVIR-ORAL)
Uses
Valtrex is an antiviral agent used in the treatment of herpes zoster (shingles), genital herpes and is also being used for herpes simplex (cold sores).
How to take Valtrex
Take Valtrex by mouth as directed. Take all Valtrex as prescribed. Do not skip doses or stop taking this without your doctor's approval. Stopping therapy too soon may result in ineffective treatment.
Side effects
Nausea, vomiting, headache, loss of appetite, weakness, stomach pain or dizziness may occur the first several days as your body adjusts to the medication. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if your condition does not appear to improve or you experience a worsening of symptoms while taking Valtrex.
Precautions
Tell your doctor if you have any kidney disease, blood disorders or if you have any allergies. Valtrex should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if Valtrex appears in breast milk. Consult with your doctor before breast-feeding.
Drug interactions
Tell your doctor of any over-the-counter or prescription medication you may take including cimetidine or probenecid.
Notes
Valtrex is most effective if it is started within 48 hours of when the rash first appears.
Miss dose
Try to take each dose at the scheduled time. If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Storage
Store Valtrex at room temperature between 59 and 77 degrees F (15 to 25 degrees C) away from heat and light. Keep this and all medications out of the reach of children.
VALTREX (valacyclovir hydrochloride) is the hydrochloride salt of L-valyl
ester of the antiviral drug acyclovir (ZOVIRAXň Brand, GlaxoSmithKline).
VALTREX Caplets are for oral administration. Each caplet contains
valacyclovir hydrochloride equivalent to 500 mg or 1 gram valacyclovir and the
inactive ingredients carnauba wax, colloidal silicon dioxide, crospovidone,
FD&C Blue No. 2 Lake, hypromellose, magnesium stearate, microcrystalline
cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide.
The blue, film-coated caplets are printed with edible white ink.
The chemical name of valacyclovir hydrochloride is L-valine,
2-[(2-amino-1,6-dihydro-6-oxo-9 H-purin-9-yl)methoxy]ethyl ester,
monohydrochloride. It has the following structural formula:

Valacyclovir hydrochloride is a white to off-whitepowder with the molecular
formula C13H20N6O4·HCl and a molecular weight of 360.80. The maximum solubility
in water at 25°C is 174 mg/mL. The pka’s for valacyclovir hydrochloride are
1.90, 7.47, and 9.43.
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